Effect of Stereospermum personatum, Senna obtusifolia and Amomumsubulatum extract in Hypoglycemia on Swiss Albino mice model

Abstract

Stereospermum personatum, Senna obtusifolia, and Amomum subulatum are common species throughout Bangladesh, India, Sri Lanka, Pakistan, and other Asian countries. Combined formulation (polyharbal) of the methanol extract of Stereospermum personatum leaves, Senna obtusifolia leaves pod and Amomum subulatum seeds were examined for hypoglycemic activity. The potential of the combined formulation of the methanol extract of these leaves, leaves pod, and seeds to reduce blood glucose was
examined in this study using a Swiss Albino mouse model. The polyherbal
formulation's highest dose in this experiment, 400 mg/kg body weight, dramatically lowered the blood glucose level. The remaining dosages of this polyhedral formulation when taken orally likewise had notable hypoglycemia effects. When compared to the Control mean value, the combined formulation of the methanol extract of the leaves of
Stereospermum personatum, the pod of Senna obtusifolia, and the seeds of Amomum subulatum exhibited significant oral hypoglycemic activity at various time intervals, indicating that all administered doses significantly decreased blood sugar levels.